pentobarbital will minimize the extent or result of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will lower the level or outcome of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. If coadministration having a CYP3A4 inducer is important, consider raisi